# Who flies Prague → Palermo nonstop?

**3 airlines fly Prague → Palermo nonstop: Ryanair (starts 25 Oct 2026), Smartwings (charter) and Wizz Air.**

| Airline | Routes | Book direct |
|---|---|---|
| Ryanair | Václav Havel Airport Prague (PRG) → Palermo (PMO) (Starts 25 Oct 2026) | https://www.ryanair.com/ |
| Smartwings | Václav Havel Airport Prague (PRG) → Palermo (PMO) (Charter) | https://www.smartwings.com/ |
| Wizz Air | Václav Havel Airport Prague (PRG) → Palermo (PMO) | https://wizzair.com |

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Compare fares for PRG-PMO: [Trip.com](https://www.trip.com/flights/prague-to-palermo/tickets-PRG-PMO/?allianceid=1094387&sid=2209817&trip_sub1=c4c6f3cbcbb845d69061b1005-713359) · [Aviasales](https://www.aviasales.com/search/PRG1011PMO1?marker=713359). Affiliate links (Trip.com, Aviasales): picktheflight may earn a commission. It never changes the price or which airlines are listed.

On picktheflight: https://picktheflight.com/?from=PRG&to=PMO · JSON: https://picktheflight.com/intents/PRG/PMO

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Data built 2026-10-19 from airline schedule tables on Wikipedia ("Airlines and destinations"), matched by exact airport article; airline booking sites from Wikidata. Schedules change. Confirm the flight on the airline's own site before booking.